The first launch of the European Space Agency’s (ESA) new Vega-C launch vehicle lifted off from the Guiana Space Centre in Kourou, French Guiana, on 13 July 2022, at 13:13 UTC (10:13 local time). The main payload for the maiden flight (VV21) is LARES-2, a scientific mission of the Italian Space Agency (ASI), while six CubeSats make a secondary payload package: AstroBio CubeSat, Greencube, ALPHA, Trisat-R, MTCube-2 and Celesta. Vega-C is an upgraded and more powerful version of the current Vega launch vehicle, with 800 kg more payload performance. Vega-C features a new, more powerful first stage (P120C), a new second stage (Zefiro-40), the same third stage (Zefiro-9) as used on Vega and an improved re-ignitable upper stage (AVUM+).